China (Mainland)
Hot Sale/High Purity 99% 1421373-66-1 in bulk supply CAS NO.1421373-66-1
- FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
- Min.Order: 25 Metric Ton
- Payment Terms: L/C,D/P,T/T,MoneyGram
- Available Specifications:
1(1-25)Kilogram
- Product Details
Keywords
- Hot Sale 1421373-66-1
- High Purity 99% 1421373-66-1
- 1421373-66-1 in bulk supply
Quick Details
- ProName: Hot Sale/High Purity 99% 1421373-66-1 ...
- CasNo: 1421373-66-1
- Molecular Formula: C28H33N7O2.CH4O3S
- Appearance: white crystallized powder
- Application: Osimertinib mesylate; AZD-9291
- DeliveryTime: on month
- PackAge: 25 kilogram card board barrels,lined w...
- Port: any chinese port or airport
- ProductionCapacity: 20/30/40/50 Kilogram/Month
- Purity: 99%
- Storage: Dry and ventilated
- Transportation: by sea or by airport
- LimitNum: 25 Metric Ton
Superiority
Hot Sale/High Purity 99% 1421373-66-1 in bulk supply
| AZD-9291 (Mesylate) Basic information |
| Product Name: | AZD-9291 (Mesylate) |
| Synonyms: | AZD-9291 (Mesylate);N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);AZD-9291 mesylate N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);Osimertinib mesylate;Mereletinib mesylate;Osimertinib;N-[2-(2-dimethylaminoethylmethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide mesylate salt;Osimertinib Mesylate(AZD9291) |
| CAS: | 1421373-66-1 |
| MF: | C28H33N7O2.CH4O3S |
Details
Hot Sale/High Purity 99% 1421373-66-1 in bulk supply
Shanghai topchem Co., LTD and integrated high-tech enterprise composed with Production , R&D and trading , Specialized in Quinolones Api and intermediatesVeterinary drugs and suppply CMO serviece for suctomers. 1.good service, high quality with competitive price. 2.fast and safe deliver0y. 3.we have clients throughhout the world 4.exported areas: eurpore, southeast asia the middle east, south america and some other countries and areas. 5. Have our own r&d group.
What is AZD9291?
Osimertinib (previously known as mereletinib or AZD9291) is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor drug.
AZD9291 is a Kinase Inhibitor. The mechanism of action of osimertinib is as a Kinase Inhibitor, and Cytochrome P450 3A Inhibitor, and Cytochrome P450 3A4 Inducer, and Cytochrome P450 1A2 Inducer, and Breast Cancer Resistance Protein Inhibitor.
As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced when compared to non-selective EGFR inhibitors which also inhibit wild-type EGFR.
AZD9291 is a Kinase Inhibitor. The mechanism of action of osimertinib is as a Kinase Inhibitor, and Cytochrome P450 3A Inhibitor, and Cytochrome P450 3A4 Inducer, and Cytochrome P450 1A2 Inducer, and Breast Cancer Resistance Protein Inhibitor.
As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced when compared to non-selective EGFR inhibitors which also inhibit wild-type EGFR.
Function of AZD9291
AZD9291 used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC). Osimertinib is associated with a moderate rate of serum aminotransferase elevations during therapy and rare instances of clinically apparent acute liver injury.