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Home > Products >  global AZD-9291/factory Osimertinib mesylate/1421373-66-1 Good Supplier In China

global AZD-9291/factory Osimertinib mesylate/1421373-66-1 Good Supplier In China CAS NO.1421373-66-1

  • FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
  • Min.Order: 25 Metric Ton
  • Payment Terms: L/C,D/P,T/T,
  • Available Specifications:

    1(1-25)Kilogram

  • Product Details

Keywords

  • global AZD-9291
  • factory Osimertinib mesylate
  • 1421373-66-1 Good Supplier In China

Quick Details

  • ProName: global AZD-9291/factory Osimertinib me...
  • CasNo: 1421373-66-1
  • Molecular Formula: C28H33N7O2.CH4O3S
  • Appearance: white crystallized powder
  • Application: Osimertinib mesylate; AZD-9291
  • DeliveryTime: on month
  • PackAge: 25 kilogram card board barrels,lined w...
  • Port: any chinese port or airport
  • ProductionCapacity: 20/30/40/50 Kilogram/Month
  • Purity: 99%
  • Storage: Dry and ventilated
  • Transportation: by sea or by airport
  • LimitNum: 25 Metric Ton

Superiority

global AZD-9291/factory Osimertinib mesylate/1421373-66-1 Good Supplier In China

 

AZD-9291 (Mesylate) Basic information
Product Name: AZD-9291 (Mesylate)
Synonyms: AZD-9291 (Mesylate);N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);AZD-9291 mesylate N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate (1:1);Osimertinib mesylate;Mereletinib mesylate;Osimertinib;N-[2-(2-dimethylaminoethylmethylamino)-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide mesylate salt;Osimertinib Mesylate(AZD9291)
CAS: 1421373-66-1
MF: C28H33N7O2.CH4O3S

 

Details

global AZD-9291/factory Osimertinib mesylate/1421373-66-1 Good Supplier In China

Shanghai topchem Co., LTD and integrated high-tech enterprise composed with Production , R&D and trading , Specialized in Quinolones Api and intermediatesVeterinary drugs and suppply CMO serviece for suctomers.                                                                                      1.good service, high quality with competitive price.   2.fast and safe deliver0y. 3.we have clients throughhout the world 4.exported areas: eurpore, southeast asia the middle east, south america and some other countries and areas. 5. Have our own r&d group.

What is AZD9291?

Osimertinib (previously known as mereletinib or AZD9291) is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor drug.

AZD9291 is a Kinase Inhibitor. The mechanism of action of osimertinib is as a Kinase Inhibitor, and Cytochrome P450 3A Inhibitor, and Cytochrome P450 3A4 Inducer, and Cytochrome P450 1A2 Inducer, and Breast Cancer Resistance Protein Inhibitor.

As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced when compared to non-selective EGFR inhibitors which also inhibit wild-type EGFR.

Function of AZD9291

AZD9291 used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC). Osimertinib is associated with a moderate rate of serum aminotransferase elevations during therapy and rare instances of clinically apparent acute liver injury.

 

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